Temporal profile of improvement of tardive dystonia after globus pallidus deep brain stimulation.

ABSTRACT:

Background

Several case reports and small series have indicated that tardive dystonia is responsive to globus pallidus deep brain stimulation. Whether different subtypes or distributions of tardive dystonia are associated with different outcomes remains unknown.

Methods

We assessed the outcomes and temporal profile of improvement of eight tardive dystonia patients who underwent globus pallidus deep brain stimulation over the past six years through record review. Due to the retrospective nature of this study, it was not blinded or placebo controlled.

Results

Consistent with previous studies, deep brain stimulation improved the overall the Burke-Fahn-Marsden motor scores by 85.1 ± 13.5%. The distributions with best responses in descending order were upper face, lower fa

SUBMITTER: Shaikh AG 

PROVIDER: S-EPMC4879955 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature