Programmatic Management of Drug-Resistant Tuberculosis: An Updated Research Agenda.

ABSTRACT:

Introduction

There are numerous challenges in delivering appropriate treatment for multidrug-resistant tuberculosis (MDR-TB) and the evidence base to guide those practices remains limited. We present the third updated Research Agenda for the programmatic management of drug-resistant TB (PMDT), assembled through a literature review and survey.

Methods

Publications citing the 2008 research agenda and normative documents were reviewed for evidence gaps. Gaps were formulated into questions and grouped as in the 2008 research agenda: Laboratory Support, Treatment Strategy, Programmatically Relevant Research, Epidemiology, and Management of Contacts. A survey was distributed through snowball sampling to identify research priorities. Respondent priority rankings were scored and sum

SUBMITTER: Mitnick CD 

PROVIDER: S-EPMC4880345 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature