Task-specific versus generalized mnemonic representations in parietal and prefrontal cortices.

ABSTRACT: Our ability to learn a wide range of behavioral tasks is essential for responding appropriately to sensory stimuli according to behavioral demands, but the underlying neural mechanism has been rarely examined by neurophysiological recordings in the same subjects across learning. To understand how learning new behavioral tasks affects neuronal representations, we recorded from posterior parietal cortex (PPC) before and after training on a visual motion categorization task. We found that categorization training influenced cognitive encoding in PPC, with a marked enhancement of memory-related delay-period encoding during the categorization task that was absent during a motion discrimination task before categorization training. In contrast, the prefrontal cortex (PFC) exhibited strong delay-pe

SUBMITTER: Sarma A 

PROVIDER: S-EPMC4880358 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature