Combinatorial development of antibacterial Zr-Cu-Al-Ag thin film metallic glasses.

ABSTRACT: Metallic alloys are normally composed of multiple constituent elements in order to achieve integration of a plurality of properties required in technological applications. However, conventional alloy development paradigm, by sequential trial-and-error approach, requires completely unrelated strategies to optimize compositions out of a vast phase space, making alloy development time consuming and labor intensive. Here, we challenge the conventional paradigm by proposing a combinatorial strategy that enables parallel screening of a multitude of alloys. Utilizing a typical metallic glass forming alloy system Zr-Cu-Al-Ag as an example, we demonstrate how glass formation and antibacterial activity, two unrelated properties, can be simultaneously characterized and the optimal composition can be

SUBMITTER: Liu Y 

PROVIDER: S-EPMC4882501 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature