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New guaiane sesquiterpenes and furanocoumarins from Notopterygium incisum.


ABSTRACT: In addition to twenty-nine known compounds, two new guaiane sesquiterpenes and two new furanocoumarins were isolated from the chloroform extract of the rhizomes of Notopterygium incisum. The new structures were elucidated by means of spectroscopic methods including 2 D NMR techniques and mass spectrometry to be 8 beta-acetoxy-4 alpha,6 alpha-dihydroxy-1 alpha,5 alpha( H)-guai-9-ene (incisumdiol A, 1), 4 alpha,6 alpha-dihydroxy-1 alpha,5 alpha( H)-guai-9-ene (incisumdiol B, 2), 5-[(2 E,5 Z)-7-hydroxy-3,7-dimethyl-2,5-octadienoxy]psoralene ( 3) and 5-[(2,5)-epoxy-3-hydroxy-3,7-dimethyl-6-octenoxy]psoralene ( 4).

SUBMITTER: Wu SB 

PROVIDER: S-EPMC4883698 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature

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New guaiane sesquiterpenes and furanocoumarins from Notopterygium incisum.

Wu Shi-Biao SB   Zhao Yun Y   Fan Hui H   Hu Ying-He YH   Hamann Mark T MT   Peng Jiang-Nan JN   Starks Courtney M CM   O'Neil-Johnson Mark M   Hu Jin-Feng JF  

Planta medica 20081107 15


In addition to twenty-nine known compounds, two new guaiane sesquiterpenes and two new furanocoumarins were isolated from the chloroform extract of the rhizomes of Notopterygium incisum. The new structures were elucidated by means of spectroscopic methods including 2 D NMR techniques and mass spectrometry to be 8 beta-acetoxy-4 alpha,6 alpha-dihydroxy-1 alpha,5 alpha( H)-guai-9-ene (incisumdiol A, 1), 4 alpha,6 alpha-dihydroxy-1 alpha,5 alpha( H)-guai-9-ene (incisumdiol B, 2), 5-[(2 E,5 Z)-7-hyd  ...[more]

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