Change in fasting plasma glucose and incident type 2 diabetes mellitus: results from a prospective cohort study.

ABSTRACT:

Objective

To investigate the association between changes in fasting plasma glucose (FPG) values and incident type 2 diabetes (T2D) in a cohort of the Iranian population.

Design

Prospective cohort study.

Setting

This study was conducted within the framework of the Tehran Lipid and Glucose Study (TLGS) to investigate the association between change in FPG between baseline examination (1999-2001) and the second visit (2002-2005) with incident T2D.

Participants

A total of 3981 non-diabetic participants aged ≥20 years.

Outcome measure

T2D was defined if the participant was using antidiabetic drugs or if FPG was ≥7 mmol/L or if the 2 h post-challenge plasma glucose (2-hPCG) was ≥11.1 mmol/L.

Results

During a median follow-up of 6.17 years, after the seco

SUBMITTER: Mozaffary A 

PROVIDER: S-EPMC4885425 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature