Correlation of pretreatment 18F-FDG uptake with clinicopathological factors and prognosis in patients with newly diagnosed diffuse large B-cell lymphoma.

ABSTRACT:

Objectives

The aim of this study is to determine the correlation of pretreatment fluorine-18 fluorodeoxyglucose uptake with clinicopathological factors and its prognostic value in patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL).

Patients and methods

A cohort of 162 patients with newly diagnosed DLBCL who had undergone pretreatment PET/computed tomography was retrospectively reviewed. The relationship of pretreatment maximum standard uptake value (SUVmax) with clinical factors, molecular markers, and efficacy was evaluated. The value of SUVmax in predicting progression-free survival (PFS) and overall survival was analyzed.

Results

In all, 72.9% of the patients received R-CHOP treatment; the rest received CHOP chemotherapy. The median follow-up durat

SUBMITTER: Huang H 

PROVIDER: S-EPMC4885594 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature