Higher oily fish consumption in late pregnancy is associated with reduced aortic stiffness in the child at age 9 years.

ABSTRACT:

Rationale

Higher pulse wave velocity (PWV) reflects increased arterial stiffness and is an established cardiovascular risk marker associated with lower long-chain n-3 polyunsaturated fatty acid intake in adults. Experimentally, maternal fatty acid intake in pregnancy has lasting effects on offspring arterial stiffness.

Objective

To examine the association between maternal consumption of oily fish, a source of long-chain n-3 polyunsaturated fatty acids, in pregnancy and child's aortic stiffness age 9 years.

Methods and results

In a mother-offspring study (Southampton Women's Survey), the child's descending aorta PWV was measured at the age of 9 years using velocity-encoded phase-contrast MRI and related to maternal oily fish consumption assessed prospectively during pr

SUBMITTER: Bryant J 

PROVIDER: S-EPMC4886834 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature