Critical Appraisal of Evidence for Improving Gait Speed in People with Multiple Sclerosis: Dalfampridine Versus Gait Training.

ABSTRACT:

Background

Research has not yet compared the treatment effects of dalfampridine with traditional rehabilitation of gait impairments in multiple sclerosis (MS). The purpose of this review was to critically appraise the evidence for dalfampridine and gait training for increasing gait speed in people with MS.

Methods

A systematic search of the research literature was conducted. Consideration was given to only randomized controlled trials (RCTs), systematic reviews, and meta-analyses. For selection of gait training studies, only studies involving task-specific gait training interventions and measuring treatment effects on gait speed were considered.

Results

Treatment effects on gait speed were extracted from four studies examining the efficacy of dalfampridine and six gai

SUBMITTER: Plummer P 

PROVIDER: S-EPMC4886996 | biostudies-literature | 2016 May-Jun

REPOSITORIES: biostudies-literature