Tremor in progressive supranuclear palsy.

ABSTRACT:

Introduction

Tremor is thought to be a rare feature of progressive supranuclear palsy (PSP).

Methods

We retrospectively reviewed the database of the CurePSP brain bank at Mayo Clinic Florida to retrieve all available clinical information for PSP patients. All patients underwent a standard neuropathological assessment and an immunohistochemical evaluation for tau and α-synuclein. DNA was genotyped for the MAPT H1/H2 haplotype.

Results

Of the 375 PSP patients identified, 344 had a documented presence or absence of tremor, which included 146 (42%) with tremor, including 29 (20%) with postural/action tremors, 16 (11%) with resting tremor, 7 (5%) with intention tremor, 20 (14%) with a combination of different types of tremor, and 74 (51%) patients who had tremor at some po

SUBMITTER: Fujioka S 

PROVIDER: S-EPMC4887294 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature