Effects of Mobility and Cognition on Risk of Mortality in Women in Late Life: A Prospective Study.

ABSTRACT:

Background

This study examines the effects of mobility and cognition on mortality risk in women late in life.

Methods

A prospective study was conducted among 1,495 women (mean age 87.6 years) participating in the Study of Osteoporotic Fractures Year 20 examination (2006-2008). Mobility (ascertained by Short Physical Performance Battery [SPPB]) was categorized as poor (SPPB 0-3, n = 312), intermediate (SPPB 4-9, n = 799), or good (SPPB 10-12, n = 384). Cognitive status (adjudicated based on neuropsychological tests) was classified as normal (n = 873), mild cognitive impairment (n = 354), or dementia (n = 268). Deaths (n = 749) were identified from Year 20 through July 31, 2014 (average follow-up 4.9 years).

Results

There was not strong evidence of an interaction betwee

SUBMITTER: Ensrud KE 

PROVIDER: S-EPMC4888393 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature