Association Between Hyponatremia and Higher Bronchiolitis Severity Among Children in the ICU With Bronchiolitis.

ABSTRACT:

Background and objectives

It remains unclear whether hyponatremia independently predicts a higher severity of bronchiolitis in children. The objective of this study was to investigate the association between hyponatremia and bronchiolitis severity in children hospitalized in the ICU for bronchiolitis.

Methods

We conducted a 16-center, prospective cohort study of hospitalized children aged <2 years with bronchiolitis during the winters of 2007 through 2010. Patients were classified into 2 groups (normonatremic [135-145 mEq/L] and hyponatremic [<135 mEq/L]) based on the first-measured serum sodium concentration on the day of hospitalization. Outcomes were use of mechanical ventilation and ICU length of stay (LOS). To examine the association of sodium status with outcomes, we f

SUBMITTER: Hasegawa K 

PROVIDER: S-EPMC4888787 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature