Associations Between Cerebellar Subregional Morphometry and Alcoholism History in Men and Women.

ABSTRACT:

Background

Alcoholism has been linked to deficits in cognitive, behavioral, and emotional functions, and the cerebellum is important for optimal functioning of these abilities. However, little is known about how individual differences such as gender and drinking history might influence regional cerebellar abnormalities.

Methods

Volumetric analyses of the cerebellum and its subregions were performed in relation to the interaction of gender and measures of drinking history. Structural magnetic resonance imaging scans of 44 alcoholic individuals (23 men) and 39 nonalcoholic controls (18 men) were obtained. In addition to measuring total cerebellar gray and white matter volumes, we measured 64 individual cerebellar parcellation units, as well as functionally defined a priori reg

SUBMITTER: Sawyer KS 

PROVIDER: S-EPMC4889497 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature