Brain functional and anatomical changes in chronic prostatitis/chronic pelvic pain syndrome.

ABSTRACT:

Purpose

Research into the pathophysiology of chronic prostatitis/chronic pelvic pain syndrome has primarily focused on markers of peripheral dysfunction. We present the first neuroimaging investigation to our knowledge to characterize brain function and anatomy in chronic prostatitis/chronic pelvic pain syndrome.

Materials and methods

We collected data from 19 male patients with chronic prostatitis/chronic pelvic pain syndrome, and 16 healthy age and gender matched controls. Functional magnetic resonance imaging data were obtained from 14 patients with chronic prostatitis/chronic pelvic pain syndrome as they rated spontaneous pain inside the scanner. Group differences (16 patients per group) in gray matter total volume and regional density were evaluated using voxel-based mo

SUBMITTER: Farmer MA 

PROVIDER: S-EPMC4889821 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature