Short-term treatment outcomes in human immunodeficiency virus type-1 and hepatitis B virus co-infections.

ABSTRACT:

Background

Co-infection of HIV with HBV is common in West Africa but little information is available on the effects of HBV on short-term therapy for HIV patients. A 28 day longitudinal study was conducted to examine short-term antiretroviral therapy (ART) outcomes in HIV infected individuals with HBV co-infection.

Methods

Plasma from 18 HIV infected individuals co-infected with HBV and matched controls with only HIV infection were obtained at initiation, and 7 and 28 days after ART. HIV-1 viral load changes were monitored. Clinical and demographic data were also obtained from patient folders, and HIV-1 drug resistance mutation and subtype analysis performed.

Results

The presence of HBV co-infection did not significantly affect HIV-1 viral load changes within 7 or 28 d

SUBMITTER: Sagoe KW 

PROVIDER: S-EPMC4890471 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature