Impact of MR-Based Attenuation Correction on Neurologic PET Studies.

ABSTRACT:

Unlabelled

Hybrid PET and MR scanners have become a reality in recent years, with the benefits of reduced radiation exposure, reduction of imaging time, and potential advantages in quantification. Appropriate attenuation correction remains a challenge. Biases in PET activity measurements were demonstrated using the current MR-based attenuation-correction technique. We aimed to investigate the impact of using a standard MR-based attenuation correction technique on the clinical and research utility of a PET/MR hybrid scanner for amyloid imaging.

Methods

Florbetapir scans were obtained for 40 participants on a hybrid scanner with simultaneous MR acquisition. PET images were reconstructed using both MR- and CT-derived attenuation maps. Quantitative analysis was performed for bot

SUBMITTER: Su Y 

PROVIDER: S-EPMC4891225 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature