Health-Related Quality of Life After Pancreatectomy: Results From a Randomized Controlled Trial.

ABSTRACT:

Background

A recent prospective randomized trial demonstrated that prophylactic pasireotide reduces the incidence of pancreatic complications (PC) after resection. This secondary analysis aimed to describe quality of life (QoL) before and after resection, to characterize the impact of PC on QoL, and to assess whether pasireotide improves QoL.

Methods

A randomized, double-blind, placebo-controlled trial of preoperative pasireotide in patients undergoing pancreatectomy was conducted. Participants completed the European Organization for Research and Treatment of Cancer (EORTC) C30 and PAN26 modules preoperatively and on postoperative days 14 and 60. Scores were compared using t tests. The percentage of patients with clinically important worsening (a decline ≥0.5 times the basel

SUBMITTER: Eaton AA 

PROVIDER: S-EPMC4891251 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature