Epidemiology and transmission characteristics of human adenovirus type 7 caused acute respiratory disease outbreak in military trainees in East China.

ABSTRACT:

Background

Human adenovirus type 7 (HAdV7) is globally attracting great concern as its high morbidity and severity in respiratory diseases, especially in Asia.

Objective

To investigate the clinical and epidemiologic characteristics of HAdV7 infection outbreak in East China.

Methods

The clinical samples were collected from the patients of an ARD outbreak in East Chinafor the detection of causative pathogens by multiplex PCR. The molecular type of human adenovirus isolates were identified by sequencing and homologous comparison based on their hexon genes. The spatiotemporal dynamics of global HAdV7 was investigated using the phylogenetic and phylogeographic analyses. Total 67 referenced HAdV7 hexon sequences (>800 bp) from GenBank were selected for constructing the maxi

SUBMITTER: Cheng J 

PROVIDER: S-EPMC4891446 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature