Association between dietary inflammatory potential and breast cancer incidence and death: results from the Women's Health Initiative.

ABSTRACT:

Background

Diet modulates inflammation and inflammatory markers have been associated with cancer outcomes. In the Women's Health Initiative, we investigated associations between a dietary inflammatory index (DII) and invasive breast cancer incidence and death.

Methods

The DII was calculated from a baseline food frequency questionnaire in 122 788 postmenopausal women, enrolled from 1993 to 1998 with no prior cancer, and followed until 29 August 2014. With median follow-up of 16.02 years, there were 7495 breast cancer cases and 667 breast cancer deaths. We used Cox regression to estimate multivariable-adjusted hazards ratios (HRs) and 95% confidence intervals (95% CIs) by DII quintiles (Q) for incidence of overall breast cancer, breast cancer subtypes, and deaths from breast c

SUBMITTER: Tabung FK 

PROVIDER: S-EPMC4891517 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature