Associations between weight change and biomarkers of cardiometabolic risk in South Asians: secondary analyses of the PODOSA trial.

ABSTRACT:

Background/objectives

The association of weight changes with cardiometabolic biomarkers in South Asians has been sparsely studied.

Subjects/methods

We measured cardiometabolic biomarkers at baseline and after 3 years in the Prevention of Diabetes and Obesity in South Asians Trial. We investigated the effect of a lifestyle intervention on biomarkers in the randomized groups. In addition, treating the population as a single cohort, we estimated the association between change in weight and change in biomarkers.

Results

Complete data were available at baseline and after 3 years in 151 participants. At 3 years, there was an adjusted mean reduction of 1·44 kg (95% confidence interval (95% CI): 0.18-2.71) in weight and 1.59 cm (95% CI: 0.08-3.09) in waist circumference in th

SUBMITTER: Welsh P 

PROVIDER: S-EPMC4892347 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature