Integrated analysis of gray and white matter alterations in attention-deficit/hyperactivity disorder.

ABSTRACT:

Background

Magnetic resonance imaging (MRI) is able to provide detailed insights into the structural organization of the brain, e.g., by means of mapping brain anatomy and white matter microstructure. Understanding interrelations between MRI modalities, rather than mapping modalities in isolation, will contribute to unraveling the complex neural mechanisms associated with neuropsychiatric disorders as deficits detected across modalities suggest common underlying mechanisms. Here, we conduct a multimodal analysis of structural MRI modalities in the context of attention-deficit/hyperactivity disorder (ADHD).

Methods

Gray matter volume, cortical thickness, surface areal expansion estimates, and white matter diffusion indices of 129 participants with ADHD and 204 participants wi

SUBMITTER: Francx W 

PROVIDER: S-EPMC4893015 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature