Preparation of Metalloporphyrin-Bound Superparamagnetic Silica Particles via "Click" Reaction.

ABSTRACT: A facile approach using click chemistry is demonstrated for immobilization of metalloporphyrins onto the surface of silica-coated iron oxide particles. Oleic-acid stabilized iron oxide nanocrystals were prepared by thermal decomposition of iron(III) acetylacetonate. Their crystallinity, morphology, and superparamagnetism were determined using X-ray diffraction, transmission electron microscopy, and a superconducting quantum interference device. Monodisperse core-shell particles were produced in the silica-coating of iron oxide via microemulsion synthesis. Surface modification of these particles was performed in two steps, which included the reaction of silica-coated iron oxide particles with 3-bromopropyltrichlorosilane, followed by azido-functionalization with sodium azide. Monoalkylated

SUBMITTER: Hollingsworth JV 

PROVIDER: S-EPMC4893945 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature