Impact of female age and nulligravidity on fecundity in an older reproductive age cohort.

ABSTRACT:

Objective

To provide female age-related estimates of fecundity and incidence of infertility by history of prior pregnancy among women 30-44 years of age.

Design

Prospective, time-to-pregnancy cohort study.

Setting

Not applicable.

Patient(s)

Women, between 30 and 44 years of age, attempting to conceive for ≤3 months, and no known history of infertility, polycystic ovarian syndrome (PCOS), or endometriosis.

Intervention(s)

Not applicable.

Main outcome measure(s)

Fecundability and incidence of infertility.

Result(s)

Compared to women aged 30-31 years, fecundability was reduced by 14% in women 34-35 years of age (fecundability ratio [FR] 0.86, 95% confidence interval [CI] 0.68-1.08), 19% in women 36-37 years of age (FR 0.81, 95% CI 0.60-1.08, 3

SUBMITTER: Steiner AZ 

PROVIDER: S-EPMC4893975 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature