A low-cost, multiplexed μECoG system for high-density recordings in freely moving rodents.

ABSTRACT:

Objective

Micro-electrocorticography (μECoG) offers a minimally invasive neural interface with high spatial resolution over large areas of cortex. However, electrode arrays with many contacts that are individually wired to external recording systems are cumbersome and make recordings in freely behaving rodents challenging. We report a novel high-density 60-electrode system for μECoG recording in freely moving rats.

Approach

Multiplexed headstages overcome the problem of wiring complexity by combining signals from many electrodes to a smaller number of connections. We have developed a low-cost, multiplexed recording system with 60 contacts at 406 μm spacing. We characterized the quality of the electrode signals using multiple metrics that tracked spatial variation, evoked-res

SUBMITTER: Insanally M 

PROVIDER: S-EPMC4894303 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature