Transmission of Hand, Foot and Mouth Disease and Its Potential Driving Factors in Hong Kong.

ABSTRACT: Hand-foot-and-mouth disease (HFMD) is a common childhood disease with substantial disease burden in Asia. Mixed results were reported on the associations between HFMD incidence and meteorological factors or school holidays, while limited studies focused on their association on transmissibility. We aimed to measure the transmissibility of HFMD and to examine its potential driving factors in Hong Kong. A likelihood-based procedure was used to estimate time-dependent effective reproduction number (Rt) based on weekly number of HFMD-associated hospitalizations from 2010 to 2014. The associations of between-year effects, depletion of susceptibles, absolute humidity and school holidays with Rt were examined using linear regression. Rt usually started increasing between early spring and summer an

SUBMITTER: Yang B 

PROVIDER: S-EPMC4895171 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature