Quantitative physicochemical analysis of acid-base balance and clinical utility of anion gap and strong ion gap in 806 neonatal calves with diarrhea.

ABSTRACT:

Background

Acid-base abnormalities in neonatal diarrheic calves can be assessed by using the Henderson-Hasselbalch equation or the simplified strong ion approach which use the anion gap (AG) or the strong ion gap (SIG) to quantify the concentration of unmeasured strong anions such as D-lactate.

Hypothesis/objectives

To determine and compare the clinical utility of AG and SIG in quantifying the unmeasured strong anion charge in neonatal diarrheic calves, and to examine the associations between biochemical findings and acid-base variables by using the simplified strong ion approach. We hypothesized that the SIG provides a more accurate prediction of unmeasured strong anions than the AG.

Animals

Eight hundred and six neonatal diarrheic calves admitted to a veterinary tea

SUBMITTER: Trefz FM 

PROVIDER: S-EPMC4895505 | biostudies-literature | 2015 Mar-Apr

REPOSITORIES: biostudies-literature