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Hypercoagulability in dogs with blastomycosis.


ABSTRACT:

Background

Blastomycosis is a potentially fatal fungal disease that most commonly affects humans and dogs. The organism causes systemic inflammation and has a predilection for the lungs. The inflammation might lead to a hypercoagulable state with microemboli in the pulmonary circulation which could contribute to inadequate oxygen exchange in infected dogs.

Hypothesis/objectives

Dogs with blastomycosis will be hypercoagulable compared with healthy case-matched controls.

Animals

Client-owned dogs with a diagnosis of blastomycosis (n = 23) and healthy case-matched controls (n = 23).

Methods

Prospective case-controlled study of client-owned dogs presented to a veterinary teaching hospital with clinical signs compatible with blastomycosis. Complete blood counts, fib

SUBMITTER: McMichael MA 

PROVIDER: S-EPMC4895520 | biostudies-literature | 2015 Mar-Apr

REPOSITORIES: biostudies-literature