Fecal microbiota of cats with naturally occurring chronic diarrhea assessed using 16S rRNA gene 454-pyrosequencing before and after dietary treatment.

ABSTRACT:

Background

The gastrointestinal (GI) microbiota has a strong impact on the health of cats and these populations can be altered in GI disease. Little research has been done to associate improvement in diarrhea with changes in GI microbiota.

Objective

To evaluate GI microbiota changes associated with diet change and related improvement in diarrhea in cats with chronic naturally occurring diarrhea.

Animals

Fifteen adult Domestic Shorthair cats with naturally occurring chronic diarrhea.

Methods

Controlled crossover dietary trial for management of diarrhea. Fecal microbiome was assessed using 454-pyrosequencing. Relationships among fecal score (FS), diet, and microbiome were explored using partial least square method, partial least square method - discriminant analy

SUBMITTER: Ramadan Z 

PROVIDER: S-EPMC4895530 | biostudies-literature | 2014 Jan-Feb

REPOSITORIES: biostudies-literature