Utilizing de Bruijn graph of metagenome assembly for metatranscriptome analysis.

ABSTRACT:

Motivation

Metagenomics research has accelerated the studies of microbial organisms, providing insights into the composition and potential functionality of various microbial communities. Metatranscriptomics (studies of the transcripts from a mixture of microbial species) and other meta-omics approaches hold even greater promise for providing additional insights into functional and regulatory characteristics of the microbial communities. Current metatranscriptomics projects are often carried out without matched metagenomic datasets (of the same microbial communities). For the projects that produce both metatranscriptomic and metagenomic datasets, their analyses are often not integrated. Metagenome assemblies are far from perfect, partially explaining why metagenome assemblies are no

SUBMITTER: Ye Y 

PROVIDER: S-EPMC4896364 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature