Identification and Analysis of Immunodominant Antigens for ELISA-Based Detection of Theileria annulata.

ABSTRACT: Tropical or Mediterranean theileriosis, caused by the protozoan parasite Theileria annulata, remains an economically important bovine disease in North Africa, Southern Europe, India, the Middle East and Asia. The disease affects mainly exotic cattle and imposes serious constraints upon livestock production and breed improvement programmes. While microscopic and molecular methods exist which are capable of detecting T. annulata during acute infection, the identification of animals in the carrier state is more challenging. Serological tests, which detect antibodies that react against parasite-encoded antigens, should ideally have the potential to identify carrier animals with very high levels of sensitivity and specificity. However, assays developed to date have suffered from a lack of sensi

SUBMITTER: Bilgic HB 

PROVIDER: S-EPMC4896419 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature