Distinct Global Brain Dynamics and Spatiotemporal Organization of the Salience Network.

ABSTRACT: One of the most fundamental features of the human brain is its ability to detect and attend to salient goal-relevant events in a flexible manner. The salience network (SN), anchored in the anterior insula and the dorsal anterior cingulate cortex, plays a crucial role in this process through rapid detection of goal-relevant events and facilitation of access to appropriate cognitive resources. Here, we leverage the subsecond resolution of large multisession fMRI datasets from the Human Connectome Project and apply novel graph-theoretical techniques to investigate the dynamic spatiotemporal organization of the SN. We show that the large-scale brain dynamics of the SN are characterized by several distinctive and robust properties. First, the SN demonstrated the highest levels of flexibility in

SUBMITTER: Chen T 

PROVIDER: S-EPMC4896426 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature