Opioid-Induced Constipation among a Convenience Sample of Patients with Cancer Pain.

ABSTRACT:

Background

Little is known regarding the burden of opioid-induced constipation (OIC) among patients who suffer from cancer-related pain.

Methods

A prospective longitudinal study was conducted among cancer patients in the United Kingdom (UK), Canada, and Germany, which included medical record data abstraction, Internet-based patient surveys, and physician surveys. Patients on daily opioid therapy (≥30 mg for ≥4 weeks) for treatment of cancer pain with self-reported OIC were recruited. Response to laxatives was defined by classifying participants into categories of laxative use and evaluating the prevalence of inadequate response. Descriptive statistics were used to evaluate outcomes, including the patient assessment of constipation-symptom (PAC-SYM), patient assessment of con

SUBMITTER: Coyne KS 

PROVIDER: S-EPMC4896913 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature