Detection of reassortant avian influenza A (H11N9) virus in environmental samples from live poultry markets in China.

ABSTRACT:

Background

Avian influenza viruses have caused human infection and posed the pandemic potential. Live poultry markets are considered as a source of human infection with avian influenza viruses. Avian influenza routine surveillance of live poultry markets is taken annually in China. We isolated the 2 H11N9 influenza virus from the surveillance program. To better understand the risk caused by these new viruses, we characterize the genetic and pathogenicity of the two viruses.

Methods

Viral isolation was conducted with specific pathogen-free (SPF) embryonated chicken eggs. Whole genome was sequenced, and phylogenetic analysis was conducted.

Results

Two H11N9 viruses were identified, with all 8 segments belonging to the Eurasian lineage. The HA, NA, M, NS and PA genes wer

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC4897819 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature