Practice advisory: Etanercept for poststroke disability: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.

ABSTRACT:

Objective

To review evidence regarding the effectiveness, safety, and tolerability of etanercept used to treat patients with poststroke disability.

Methods

We searched MEDLINE and the Cochrane Central Register of Controlled Trials for studies of adult patients with poststroke disability treated with etanercept in order to improve their functional status. We rated each study for risk of bias (Class I-IV) using the American Academy of Neurology therapeutic classification of evidence scheme. Practice recommendations were formulated on the basis of the strength of the evidence and assessments of potential benefits, potential harms, and patient preferences.

Results

Two case series were identified, and both reported clinical improvements 3 weeks following treatment across a

SUBMITTER: Gronseth GS 

PROVIDER: S-EPMC4898316 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature