Network localization of hemichorea-hemiballismus.

ABSTRACT:

Objective

To determine whether neuroanatomically heterogeneous strokes causing hemichorea-hemiballismus localize to a common functional network.

Methods

We identified 29 cases of lesion-induced hemichorea-hemiballismus from the literature and mapped each lesion volume onto a reference brain. Using a recently validated technique termed lesion network mapping, we tested whether these lesions belonged to the same functional network. To accomplish this, the network of brain regions functionally connected to each lesion was identified using a connectome dataset from healthy participants. Network maps were overlapped to identify any region functionally connected to our set of lesions. Specificity was evaluated using a case-control design; control cohorts included a group of simila

SUBMITTER: Laganiere S 

PROVIDER: S-EPMC4898318 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature