Modelling estimates of age-specific influenza-related hospitalisation and mortality in the United Kingdom.

ABSTRACT:

Background

Influenza is rarely confirmed with laboratory testing and accurate assessment of the overall burden of influenza is difficult. We used statistical modelling methods to generate updated, granular estimates of the number/rate of influenza-attributable hospitalisations and deaths in the United Kingdom. Such data are needed on a continuing basis to inform on cost-benefit analyses of treatment interventions, including vaccination.

Methods

Weekly age specific data on hospital admissions (1997-2009) and on deaths (1997-2009) were obtained from national databases. Virology reports (1996-2009) of influenza and respiratory syncytial virus detections were provided by Public Health England. We used an expanded set of ICD-codes to estimate the burden of illness attributable to

SUBMITTER: Matias G 

PROVIDER: S-EPMC4898386 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature