Sex differences in hospital mortality following acute myocardial infarction in China: findings from a study of 45 852 patients in the COMMIT/CCS-2 study.

ABSTRACT:

Objective

To assess the sex difference in hospital mortality following ST elevation myocardial infarction (STEMI) in China.

Design

Observational study of patients enrolled into a large trial, adjusting for age, presenting characteristics and hospital treatments using logistic regression.

Settings

1250 hospitals in China during 1999-2005.

Patients

42 683 STEMI patients, including 31 309 men and 11 374 women.

Intervention

In the original trial, all patients received 162 mg of aspirin plus 75 mg of clopidogrel daily or matching placebo and metoprolol (15 mg intravenous then 200 mg oral daily) or matching placebo. All other aspects of patients' treatments were at the discretion of responsible doctors.

Major outcomes

Hospital mortality from any cause d

SUBMITTER: Chen Y 

PROVIDER: S-EPMC4898572 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature