Novel Dielectric Coagulometer Identifies Hypercoagulability in Patients with a High CHADS2 Score without Atrial Fibrillation.

ABSTRACT:

Background

Recent reports showed that the CHADS2 score predicted the risk of strokes in patients without atrial fibrillation (AF). Although the hypercoagulability may contribute to the thrombogenesis, it has not been fully investigated due to a lack of a sensitive evaluation modality. Recently a novel dielectric blood coagulometry (DBCM) was invented for evaluating the coagulability by measuring the temporal change in whole blood dielectric permittivity.

Objective

We evaluated the utility of the DBCM for identifying the coagulability.

Patients/methods

For fundamental experiments, 133 citrated blood samples were drawn from subjects with or without heparin administration. A DBCM analysis was performed to find the adequate coagulation index, and to delineate its measurem

SUBMITTER: Hasegawa Y 

PROVIDER: S-EPMC4898832 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature