Development and Validation of Risk Models to Select Ever-Smokers for CT Lung Cancer Screening.

ABSTRACT:

Importance

The US Preventive Services Task Force (USPSTF) recommends computed tomography (CT) lung cancer screening for ever-smokers aged 55 to 80 years who have smoked at least 30 pack-years with no more than 15 years since quitting. However, selecting ever-smokers for screening using individualized lung cancer risk calculations may be more effective and efficient than current USPSTF recommendations.

Objective

Comparison of modeled outcomes from risk-based CT lung-screening strategies vs USPSTF recommendations.

Design, setting, and participants

Empirical risk models for lung cancer incidence and death in the absence of CT screening using data on ever-smokers from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO; 1993-2009) control group. Covar

SUBMITTER: Katki HA 

PROVIDER: S-EPMC4899131 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature