Population-specific FST values for forensic STR markers: A worldwide survey.

ABSTRACT: The interpretation of matching between DNA profiles of a person of interest and an item of evidence is undertaken using population genetic models to predict the probability of matching by chance. Calculation of matching probabilities is straightforward if allelic probabilities are known, or can be estimated, in the relevant population. It is more often the case, however, that the relevant population has not been sampled and allele frequencies are available only from a broader collection of populations as might be represented in a national or regional database. Variation of allele probabilities among the relevant populations is quantified by the population structure quantity FST and this quantity affects matching proportions. Matching within a population can be interpreted only with respect

SUBMITTER: Buckleton J 

PROVIDER: S-EPMC4899164 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature