Dynamics of biomarkers in relation to aging and mortality.

ABSTRACT: Contemporary longitudinal studies collect repeated measurements of biomarkers allowing one to analyze their dynamics in relation to mortality, morbidity, or other health-related outcomes. Rich and diverse data collected in such studies provide opportunities to investigate how various socio-economic, demographic, behavioral and other variables can interact with biological and genetic factors to produce differential rates of aging in individuals. In this paper, we review some recent publications investigating dynamics of biomarkers in relation to mortality, which use single biomarkers as well as cumulative measures combining information from multiple biomarkers. We also discuss the analytical approach, the stochastic process models, which conceptualizes several aging-related mechanisms in th

SUBMITTER: Arbeev KG 

PROVIDER: S-EPMC4899173 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature