Testicular seminoma clinical stage 1: treatment outcome on a routine care level.

ABSTRACT:

Purpose

Clinical stage 1 (CS1) testicular seminoma involves an almost 100 % disease-specific survival in controlled clinical trials. We aimed to find out whether these results can be matched in patients managed on the routine care level.

Patients, methods

In total, 725 patients with seminoma CS1 were prospectively enrolled from 130 institutions. Adjuvant management as decided by local physicians involved surveillance (n = 256), radiotherapy (41), 1× Carboplatin (362), and 2× Carboplatin (66). We registered type of management, age, duration of follow-up (F/U), relapse, rete testis invasion (RTI), and tumor size. Actuarial relapse-free survival curves were calculated for treatment modalities and stratified for tumor sizes and RTI. A Cox regression model was calculated to explo

SUBMITTER: Dieckmann KP 

PROVIDER: S-EPMC4899489 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature