Frequency and typing of Propionibacterium acnes in prostate tissue obtained from men with and without prostate cancer.

ABSTRACT:

Background

Prostate cancer is the most common cancer among men in Western countries but the exact pathogenic mechanism of the disease is still largely unknown. An infectious etiology and infection-induced inflammation has been suggested to play a role in prostate carcinogenesis and Propionibacterium acnes has been reported as the most prevalent microorganism in prostatic tissue. We investigated the frequency and types of P. acnes isolated from prostate tissue samples from men with prostate cancer and from control patients without the disease.

Methods

We included 100 cases and 50 controls in this study. Cases were men diagnosed with prostate cancer undergoing radical prostatectomy and controls were men undergoing surgery for bladder cancer without any histological findings of

SUBMITTER: Davidsson S 

PROVIDER: S-EPMC4899914 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature