Hormonal regulatory mechanisms in obese children and adolescents after previous weight reduction with a lifestyle intervention: maintain - paediatric part - a RCT from 2009-15.

ABSTRACT:

Background

Weight loss improves cardiovascular risk factors and "quality of life". Most therapeutic approaches fail to induce a sustained weight loss and most individuals undergo weight regain. In this paper the comprehensive design of the "MAINTAIN" study, all assessments as well as the one year lifestyle intervention will be outlined in detail.

Methods/design

One-center randomized controlled trial with seven assessment time points conducted 2009-2015. For the randomization eight groups were distinguished in a list to allocate intervention or control group: Females and males either pre-pubertal or pubertal and with a BMI-SDS under or over 2.5.

Setting

Weight loss at a residential weight reduction programme Berlin/Brandenburg and intervention at a paediatric outpatien

SUBMITTER: Bau AM 

PROVIDER: S-EPMC4901466 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature