Viable Compositional Analysis of an Eleven Species Oral Polymicrobial Biofilm.

ABSTRACT:

Purpose

Polymicrobial biofilms are abundant in clinical disease, particularly within the oral cavity. Creating complex biofilm models that recapitulate the polymicrobiality of oral disease are important in the development of new chemotherapeutic agents. In order to do this accurately we require the ability to undertake compositional analysis, in addition to determine individual cell viability, which is difficult using conventional microbiology. The aim of this study was to develop a defined multispecies denture biofilm model in vitro, and to assess viable compositional analysis following defined oral hygiene regimens.

Methods

An in vitro multispecies denture biofilm containing various oral commensal and pathogenic bacteria and yeast was created on poly (methyl methacrylate)

SUBMITTER: Sherry L 

PROVIDER: S-EPMC4902011 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature