Depression and Frailty in Late Life: Evidence for a Common Vulnerability.

ABSTRACT:

Objectives

The study purpose is to estimate the correlation between depression and competing models of frailty, and to determine to what degree the comorbidity of these syndromes is determined by shared symptomology.

Methods

Data come from the 2010 Health and Retirement Study. Analysis was limited to community-dwelling participants 65 and older (N = 3,453). Depressive symptoms were indexed by the 8-item Centers for Epidemiologic Studies Depression (CESD) scale. Frailty was indexed by 3 alternative conceptual models: (a) biological syndrome, (b) frailty index, and (c) functional domains. Confirmatory factor analysis (CFA) was used to estimate the correlation between depression and each model of frailty.

Results

Each of the 3 frailty latent factors was significantly cor

SUBMITTER: Lohman M 

PROVIDER: S-EPMC4903031 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature