The genetic relationship between cannabis and tobacco cigarette use in European- and African-American female twins and siblings.

ABSTRACT:

Background

Use of cigarettes and cannabis frequently co-occurs. We examine the role of genetic and environmental influences on variation in and covariation between tobacco cigarette and cannabis use across European-American (EA) and African-American (AA) women.

Methods

Data on lifetime cannabis and cigarette use were drawn from interviews of 956 AA and 3557 EA young adult female twins and non-twin same sex female full siblings. Twin modeling was used to decompose variance in and covariance between cigarette and cannabis use into additive genetic, shared, special twin and non-shared environmental sources.

Results

Cigarette use was more common in EAs (75.3%, 95% C.I. 73.8-76.7%) than AAs (64.2%, 95% C.I. 61.2-67.2%) while cannabis use was marginally more commonly report

SUBMITTER: Agrawal A 

PROVIDER: S-EPMC4904709 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature