Iron Supplementation in Iron-Replete and Nonanemic Pregnant Women in Tanzania: A Randomized Clinical Trial.

ABSTRACT:

Importance

Anemia is common in pregnancy and increases the risk of adverse outcomes. Iron deficiency is a leading cause of anemia in sub-Saharan Africa, and iron supplementation is the standard of care during pregnancy; however, recent trials among children have raised concerns regarding the safety of iron supplementation in malaria-endemic regions. There is limited evidence on the safety of iron supplementation during pregnancy in these areas.

Objective

To evaluate the safety and efficacy of iron supplementation during pregnancy in a malaria-endemic region.

Design, setting, and participants

We conducted a randomized, double-blind, placebo-controlled clinical trial among pregnant women presenting for antenatal care in Dar es Salaam, Tanzania, from September 28, 2010,

SUBMITTER: Etheredge AJ 

PROVIDER: S-EPMC4904713 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature