Three-Year Outcomes of Bariatric Surgery vs Lifestyle Intervention for Type 2 Diabetes Mellitus Treatment: A Randomized Clinical Trial.

ABSTRACT:

Importance

Questions remain about the role and durability of bariatric surgery for type 2 diabetes mellitus (T2DM).

Objective

To compare the remission of T2DM following surgical and nonsurgical treatments.

Design, setting, and participants

In this 3-arm randomized clinical trial conducted at the University of Pittsburgh Medical Center from October 1, 2009, to June 26, 2014, in Pittsburgh, Pennsylvania, outcomes were assessed 3 years after treating 61 obese participants aged 25 to 55 years with T2DM. Analysis was conducted with an intent-to-treat population.

Interventions

Participants were randomized to either an intensive lifestyle weight loss intervention for 1 year followed by a low-level lifestyle intervention for 2 years or surgical treatments (Roux-en-Y ga

SUBMITTER: Courcoulas AP 

PROVIDER: S-EPMC4905566 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature