Bovine coronavirus in naturally and experimentally exposed calves; viral shedding and the potential for transmission.

ABSTRACT:

Background

Bovine coronavirus (BCoV) is a widely distributed pathogen, causing disease and economic losses in the cattle industry worldwide. Prevention of virus spread is impeded by a lack of basic knowledge concerning viral shedding and transmission potential in individual animals. The aims of the study were to investigate the duration and quantity of BCoV shedding in feces and nasal secretions related to clinical signs, the presence of virus in blood and tissues and to test the hypothesis that seropositive calves are not infectious to naïve in-contact calves three weeks after BCoV infection.

Methods

A live animal experiment was conducted, with direct contact between animal groups for 24 h as challenge procedure. Four naïve calves were commingled with a group of six natural

SUBMITTER: Oma VS 

PROVIDER: S-EPMC4906604 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature